THInCR - The HPV Induced Cancer Resource
THInCR - Correlation of HPV mRNA and Cellular mRNA Expression by HPV Status
Description: The purpose of this analysis is to explore relationships between viral gene mRNA expression and expression of candidate cellular mRNAs in HPV16, HPV33, and HPV35 positive cervical (CESC) and head & neck cancers (HNSC). Select the candidate cellular mRNAs by typing the name in the input box on the top right to perform a Spearman's correlation analysis. Generated figures can be resized via dragging the right or bottom figure edges, or via the grey triangle in the bottom right edge of the figure. Heat maps can be downloaded as PNG files and the significance matrix data can be downloaded as a CSV file. Level 3 mRNA expression data from the TCGA HNSC and CESC cohorts was downloaded from the Broad Genome Data Analysis Center’s Firehose server Link . HPV16/33/35 status and viral mRNA expression was extracted from Ren et al, Oncogene 2020 DOI: 10.1038/s41388-020-01431-8
Download the Correlation Master List: Click Here
Video Guide: Click Here
Citing THInCR: Salnikov M, Gameiro SF, Zeng PYF, Barrett JW, Nichols AC, Mymryk JS. 2022. The HPV Induced Cancer Resource (THInCR): a Suite of Tools for Investigating HPV-Dependent Human Carcinogenesis. mSphere. 7(4): e0031722.
