Description: The purpose of this analysis is to compare expression of candidate cellular genes between Epstein-Barr virus (EBV)-positive intestinal gastric adenocarcinomas (IGCs), EBV-negative IGCs, diffuse gastric adenocarcinomas (DGCs), mixed gastric adenocarcinomas (MGCs), chronic gastritis (CG), and normal controls (NC) sourced from Zhange et al. (Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing) DOI: 10.1136/gutjnl-2019-320368 . Select one or more (up to 10) candidate genes by typing the name in the input box on the top right and selecting the genes of interest. Generated figures can be resized via dragging the right or bottom figure edges, or via the grey triangle in the bottom right edge of the figure. Dimensional reduction, dot, violion, and feature plots plots can be downloaded as PNG or PDF files and tables summarizing log-fold change in gene expression and statistical significance can be downloaded as a CSV file.
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Citing EBV-GCR: Salnikov MY, Wang E, Christensen E, Prusinkiewicz MA, Shooshtari P, Mymryk JS. The EBV Gastric Cancer Resource (EBV-GCR): A Suite of Tools for Investigating EBV-Associated Human Gastric Carcinogenesis. Viruses. 2023 Mar 27;15(4):853.